Tri-Mili™ is an estrogen/progestin COC, indicated for use by women to prevent pregnancy and is also indicated for the treatment of moderate acne vulgaris in females at least 15 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche.
Use Tri-Mili (ethinyl estradiol and norgestimate) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
Follow how to use as you have been told by the doctor or read the package insert.
Take Tri-Mili (ethinyl estradiol and norgestimate) at the same time of day.
Take with or without food. Take with food if it causes an upset stomach.
If you also take colesevelam, take it at least 4 hours after you take Tri-Mili (ethinyl estradiol and norgestimate).
Do not skip doses, even if you do not have sex very often.
If you throw up or have diarrhea, Tri-Mili (ethinyl estradiol and norgestimate) may not work as well to prevent pregnancy. Use an extra form of birth control, like condoms, until you check with your doctor.
If you miss 2 periods in a row, take a pregnancy test before starting a new cycle.
Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
Signs of gallbladder problems like pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; fever with chills; bloating; or very upset stomach or throwing up.
Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
Low mood (depression).
Feeling very tired or weak.
Not able to pass urine or change in how much urine is passed.
A lump in the breast, breast soreness, or nipple discharge.
Vaginal itching or discharge.
Spotting or vaginal bleeding that is very bad or does not go away.
Change in eyesight.
Loss of eyesight.
Change in how contact lenses feel in the eyes.
Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
Upset stomach or throwing up.
Feeling nervous and excitable.
Feeling tired or weak.
Period (menstrual) changes. These include spotting or bleeding between cycles.
This medicine may cause dark patches of skin on your face. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Do not take this medicine with the following medication:
dasabuvir; ombitasvir; paritaprevir; ritonavir
ombitasvir; paritaprevir; ritonavir
This medicine may also interact with the following medications:
antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin, and possibly penicillins or tetracyclines
ascorbic acid (vitamin C)
barbiturate medicines, such as phenobarbital
medicines for anxiety or sleeping problems, such as diazepam or temazepam
medicines for diabetes, including pioglitazone
ritonavir or other medicines for HIV infection or AIDS
soy isoflavones supplements
St. Johns wort
tamoxifen or raloxifene
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Symptoms of overdose may include severe nausea and vomiting, sudden/unusual vaginal bleeding.